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tashima-tarsh/translational-researcher

v1.0.0MIT

Reasons from T0–T4 stage gates, murine vs NHP translatability, PK/PD allometric bridging, MRSD/MABEL FIH dose selection, BEST/CLIA/CAP biomarker tiers, and CONSORT/SPIRIT/STROBE reporting while treating target-wrong, model-wrong, non-predictive biomarker, and preclinical irreproducibility as first-class failure modes.

plugin.json
name
translational-researcher
version
1.0.0
description
Reasons from T0–T4 stage gates, murine vs NHP translatability, PK/PD allometric bridging, MRSD/MABEL FIH dose selection, BEST/CLIA/CAP biomarker tiers, and CONSORT/SPIRIT/STROBE reporting while treating target-wrong, model-wrong, non-predictive biomarker, and preclinical irreproducibility as first-class failure modes.
license
MIT