polars-bio
High-performance genomic interval operations and bioinformatics file I/O on Polars DataFrames. Overlap, nearest, merge, coverage, complement, subtract for BED/VCF/BAM/GFF intervals. Streaming, cloud-native, faster bioframe alternative.
- Version
- 1.1
- License
- Apache-2.0
- Compatibility
- Requires Python 3.11–3.14 and polars-bio (uv pip install). Cloud I/O uses standard AWS/GCS/Azure SDK env vars when paths use s3://, gs://, or az:// URIs.
Pinned to revision 70a605012eee, so it is the text this page describes rather than whatever the author pushed since.
Pre-approved tools experimental
Experimental field. Support varies between clients, so this list is what the author declared, not what your client will enforce.
- Read
- Write
- Edit
- Bash
Files
- skills/polars-bio/SKILL.md
- skills/polars-bio/references/bioframe_migration.md
- skills/polars-bio/references/configuration.md
- skills/polars-bio/references/file_io.md
- skills/polars-bio/references/interval_operations.md
- skills/polars-bio/references/pileup_operations.md
- skills/polars-bio/references/sql_processing.md
Every link opens the file at its source, pinned to the revision this page describes.