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mondotwin/mondotwin-researcher

v0.7.4

Seven clinical-research skills on mondoTWIN's trial-registry and regulatory-guidance database: benchmark similar trials, count and compare registered trials with read-only SQL, report which endpoints and comparators the trials of an indication used and how they fared, review a protocol section against ICH, draft eligibility criteria from comparable trials, choose endpoints and estimands, and look up ICH or FDA guidance with quoted passages. Includes the mondoTWIN connector (OAuth sign-in).

endpoint-comparator-precedent

Report which primary endpoints the registered trials of an indication used and how often each succeeded or failed, by phase, and which control arms and active comparators those trials used and how they fared, from mondoTWIN's twin. Use when the user asks which endpoints work or have succeeded for a disease, for endpoint precedent or success rates by endpoint, what primary endpoint a phase 3 should use, which comparator or control arm trials in the indication used, the standard-of-care comparator, placebo versus active comparator, or what trials in an indication have measured. Descriptive precedent, not a prediction.

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