scvelo

Performs RNA velocity analysis with scVelo from spliced and unspliced single-cell RNA counts. Fits deterministic or dynamical models, examines gene phase portraits, builds velocity graphs, estimates relative latent time, and ranks velocity-associated genes. Use for directional trajectory hypotheses and kinetic-model diagnostics alongside Scanpy; velocity alone does not establish cell fate or causal drivers.

Version

2.0

License

BSD-3-Clause

Compatibility

Requires Python 3.13 for the tested stack with scvelo 0.3.4, scanpy 1.12.4, anndata 0.13.4, numpy 2.5.3 and pandas 2.3.3. Loom import requires loompy. Local H5AD analysis needs no network or credentials. The default stochastic solver is incompatible with NumPy 2.