relion

Validates and executes RELION single-particle cryo-EM refinement and half-map postprocessing. Supports STAR optics/acquisition checks, particle-stack consistency, gold-standard half sets, soft-mask validation, diagnostic Fourier shell correlation, and restart guidance.

Version

1.1

License

MIT

Compatibility

Python 3.12+ with numpy, mrcfile and starfile for bundled validation; RELION 5.0.1 CPU/MPI executables for refinement and postprocessing. Native workflows require MPI, OpenMP and an FFT library (FFTW or MKL). GPU builds require their supported accelerator stack. Network is needed for installation only.