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Reasons from flock-level feed-to-gain conversion, digestible amino acid balance, and thermal/respiratory/pathogen load through FCR/EPEF and HDEP/HOF metrics, pen-or-house mixed models, coccidiosis lesion scoring, hatchery break-out, and strain management guides while treating subclinical coccidiosis and necrotic enteritis, wet-litter footpad dermatitis, pseudoreplicated subsampling, and woody-breast myopathy as first-class failure modes.