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k-dense-ai/immunotherapy-scientist

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Reasons from antigen recognition and checkpoint circuits through CAR-T/bispecific design, ASTCT CRS/ICANS grading, flow cytometry release CQAs, iRECIST response assessment, COMPASS/TIDE biomarker modeling, and JACIE/FACT IEC accreditation while treating antigen escape, pseudoprogression, tonic signaling, and step-up CRS as first-class failure modes.