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k-dense-ai/drug-discovery-agent-skills

v1.3.0MIT

Agent Skills for small-molecule and protein therapeutics: target validation and human genetics, bioactivity and chemical space, generative design and retrosynthesis, docking, free energy and dynamics, ADMET and PK translation, protein, antibody, degrader and oligonucleotide design, and the clinical and regulatory record.

chembl

Query the ChEMBL database web services for measured bioactivity data, compound records and calculated properties, targets, assays, mechanisms of action, drug indications and warnings. Use this skill to build curated SAR or QSAR datasets for a target, look compounds up by SMILES, InChIKey, name, or ChEMBL id, run similarity and substructure searches, and check what chemistry is already known against a protein. Also trigger when a query mentions ChEMBL ids (CHEMBL...), pChEMBL values, IC50/Ki/Kd/EC50 retrieval, assay confidence scores, or ebi.ac.uk/chembl.

Version
1.0
License
MIT
Compatibility
Requires Python 3.10+ and outbound HTTPS access to www.ebi.ac.uk. The bundled scripts use only the Python standard library and need no API key. ChEMBL data is CC BY-SA 3.0; bulk analyses beyond ~100k activities should use the FTP database dump rather than the API.
Read SKILL.md at the source

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Pre-approved tools experimental

Experimental field. Support varies between clients, so this list is what the author declared, not what your client will enforce.

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